7/13/2023 0 Comments Altered skin![]() With the progression of AD, effective topical and systemic therapies are needed to reduce immune pathway activation and general inflammation. In the initial phase of AD, treatment with moisturizers improves skin barrier function and prevents the development of AD. Multiple factors, including immune dysregulation, filaggrin mutations, deficiency of antimicrobial peptides, and skin dysbiosis contribute to skin barrier defects. Skin barrier dysfunction is the initial step in the development of AD. Atopic dermatitis (AD) is the most common, complex chronic inflammatory skin disease. It plays critical roles in preventing environmental allergen penetration into the human body and responsing to microbial pathogens. It will also help to prevent pigmentation and sunspots, sensitivity causing that barrier function to become impaired, fine lines and wrinkles as a result collagen and elastin degradation and damage.The epidermis contains epithelial cells, immune cells, and microbes which provides a physical and functional barrier to the protection of human skin. There is a misconception that sunscreen/blockers only need to be used in the warmer months, at the beach or when in directly exposed to the sun and while short bouts of regular sun exposure is actually very important for our health, it can be detrimental to our skin and its impossible to know for sure who will be adversely affected so choosing and using good sun protection daily is a must. This is not only going to benefit your skin, but is essential for your wellbeing and it also helps the therapist to check on your skin, monitor changes and adjust homecare products where necessary. Develop a ritual that you follow daily and perhaps formulate a budget to help your incorporate regular visits to your skin care professional. While having in-clinic treatments regularly will definitely help, 70-80% of what you do at home, skin care, diet and lifestyle, is crucial for protecting your skin. You don’t need to spend a fortune but it does need to include high quality ingredients, so sometimes that means spending a little more than you normally would at department stores or the supermarket. Invest in some good quality skin care that has been recommended for your current skin health state. A diet high in sugars and trans fatty acidsįirstly, see a professional skin therapist and get the right advice.Abuse (overuse) of highly active skin care and over-exfoliation. ![]() Incorrect use of products or using products that are not suitable for the needs of your skin.Internal health factors and accumulation of waste products (toxins).What are some reasons your skin barrier isn’t working as it should? When we see cases like this in clinic, the first thing we will look to address in the skin is the underlying cause, followed by protection and restoration because with an impaired barrier function comes a long list of other issues, which long-term are likely to damage the skin, causing inflammation (inflammation = premature ageing). This is due to the absence or destruction of the hydrolipid barrier (a film on the surface of the skin containing sebum/oils/lipids, sweat and water) that essentially protects the skin. Other lesions (due to acne, eczema, dermatitis etc.)Ī combination of the above make the skin more susceptible to irritants and bacteria penetrating the surface.Some of the signs of an impaired skin barrier include Sometimes multiple layers are affected all the way down to the dermis, meaning your collagen and elastin can become compromised and trust me, you don’t want that. When the skins barrier function is impaired, that means the homeostasis of the stratum corneum (the outermost layer of the skin) is disrupted.
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